Sample simulated data for exposure-response with covariates

Usage

exposure.response.sample.with.cov

Format

A data frame with columns:

dose: Dose levels used for simulation of pharmacokinetics
conc: Simulated exposure
resp: Simulated pharmacodynamic response
cov1: Covariate 1 for e0
cov2: Covariate 2 for emax
cov3: Covariate 3 for ec50 (data type factor)
cov3num: Covariate 3 for ec50 (data type numeric)

Examples

exposure.response.sample
#> # A tibble: 60 × 3
#>     dose exposure response
#>    <dbl>    <dbl>    <dbl>
#>  1     0        0    17.2 
#>  2     0        0     9.78
#>  3     0        0    -8.81
#>  4     0        0     7.68
#>  5     0        0    -6.30
#>  6     0        0    14.8 
#>  7     0        0   -18.5 
#>  8     0        0    17.3 
#>  9     0        0    15.0 
#> 10     0        0    11.3 
#> # ℹ 50 more rows