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Sample simulated data for exposure-response with covariates

Usage

exposure.response.sample.with.cov

Format

A data frame with columns:

dose

Dose levels used for simulation of pharmacokinetics

conc

Simulated exposure

resp

Simulated pharmacodynamic response

cov1

Covariate 1 for e0

cov2

Covariate 2 for emax

cov3

Covariate 3 for ec50 (data type factor)

cov3num

Covariate 3 for ec50 (data type numeric)

Examples

exposure.response.sample
#> # A tibble: 60 × 3
#>     dose exposure response
#>    <dbl>    <dbl>    <dbl>
#>  1     0        0    17.2 
#>  2     0        0     9.78
#>  3     0        0    -8.81
#>  4     0        0     7.68
#>  5     0        0    -6.30
#>  6     0        0    14.8 
#>  7     0        0   -18.5 
#>  8     0        0    17.3 
#>  9     0        0    15.0 
#> 10     0        0    11.3 
#> # ℹ 50 more rows